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The goal was to investigate the efficacy of Ketorolac tromethamine diluted in saline compared to normal saline in minimizing postoperative complications, such as pain and swelling.
Ketorolac saline (10 mg/100 mL) is more effective in mitigating postoperative pain than normal saline solution (0.9% sodium chloride) in patients undergoing impacted lower third molar surgery.
The goal was to investigate the efficacy of Ketorolac tromethamine diluted in saline compared to normal saline in minimizing postoperative complications, such as pain and swelling.
In this prospective clinical study, 50 individuals scheduled for prophylactic lower third molar removal were included. Volunteers were randomly allocated to receive either Ketorolac diluted saline irrigant or plain saline irrigant (0.9% sodium chloride [NaCl] without any drug dilution). Postoperative pain and swelling were assessed in both groups at 3 time points: preoperatively, 48 hours postoperatively, and 7 days postoperatively.
Swelling was estimated via a 4-point scale, while the pain was examined via a 10-point visual analogue scale (VAS). Statistical analysis was executed utilizing IBM SPSS Statistics. An unpaired t-test was used to determine continuous variables between groups. For checking normality, the Shapiro-Wilk test was applied.
Those in the Ketorolac saline group experienced markedly lower postoperative pain scores when compared to those in the plain saline group (P=0.001). Although swelling was also reduced in the Ketorolac saline group, the difference was not statistically significant by day 7 (P=0.09), as shown in Table 1:
Ketorolac diluted saline solution proved to be a potential irrigant for postoperative pain management in surgical removal of impacted lower third molars.
Cureus
Efficacy of Ketorolac Tromethamine Diluted Saline Irrigant on Postoperative Sequelae in Patients Undergoing Lower Third Molar Impaction Surgery: A Prospective Clinical Study
Soorumsetty Ruthvik et al.
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