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This study aims to describe the perceptions of orthopedic surgeons on the efficacy of intra-articular hyaluronic acid (IA-HA), the influence of IA-HA product characteristics on its efficacy, and to identify patterns and factors related to the use of IA-HA.
This research has
been mentioned as the first paper addressing clinician’s perceptions regarding
the use of Intra- Articular Hyaluronic Acid for the treatment of knee
osteoarthritis. Here, additional research in this context needs to be done to
get further refined results.
This study aims
to describe the perceptions of orthopedic surgeons on the efficacy of
intra-articular hyaluronic acid (IA-HA), the influence of IA-HA product
characteristics on its efficacy, and to identify patterns and factors related
to the use of IA-HA. Additionally, this study examines factors that influence
IA-HA brand selection, focusing on Euflexxa® (1% sodium hyaluronate).
We developed
survey questions by reviewing the current literature and consulting with
experts on the use of IA-HA in the management of knee osteoarthritis (OA). The
survey included questions on demographics, previous experience with knee OA
treatment, opinions on different treatment methods, and where information
regarding treatments is obtained. Additionally, questions specific to opinions
regarding IA-HA and the reasoning behind these opinions were asked.
A total of 117
orthopedic surgeons and physicians completed the survey. IA-HA is most
frequently prescribed to patients with early-stage (82%) or mid-stage (82.8%)
OA, while fewer orthopedic surgeons and physicians use IA-HA for patients with
late-stage OA (57.4%). Respondents were generally uncertain of the effects that
intrinsic characteristics, such as molecular weight, cross-linking, and
production process, had on patient outcomes. Respondents typically use their
own clinical experience and results as a deciding factor in utilizing IA-HA
treatment, as well as in choosing an IA-HA brand.
Uncertainty
regarding the efficacy of IA-HA treatments is likely due to inconsistency
within clinical guidelines and the current literature. Additional research
investigating the efficacy of IA-HA treatment and how product characteristics
affect outcome and safety is required to provide clarity to the controversy
surrounding IA-HA treatment for knee OA.
Clinical Medicine Insights: Arthritis and Musculoskeletal Disorders 2016;9: 21–27
Clinicians' Perspectives on the Use of Intra-Articular Hyaluronic Acid as a Treatment for Knee Osteoarthritis: A North American, Multidisciplinary Survey
Jeffrey Rosen et al.
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