According to a recent analysis published in the journal Arthritis Care & Research, out of various knee bending forms among the individuals with knee osteoarthritis (OA), only prolonged kneeling showed a correlation with Hoffa‐synovitis prevalence on non‐contrast magnetic resonance imaging MRI.

A total of 594 subjects of age 1.5 ± 8.9 years and 30.7 ± 4.8 kg/m2 BMI selected to extract the data. A standard questionnaire and MRI OsteoArthritis Knee Scoring system were used to estimate knee-bending activities and the severity of Hoffa‐synovitis and effusion‐synovitis, respectively. The unadjusted and adjusted metabolic syndrome and physical activity logistic regression were applied for each sex. The synovitis prevalence was defined as a grade ≥2 cut‐off by grade ≥1, implemented in sensitivity analyses

A total of 62% and 59% of patients exhibited the grade ≥1 effusion‐synovitis and Hoffa‐synovitis. Only kneeling for ≥30 minutes during a single day was noticed to be related to grade ≥1 Hoffa‐synovitis prevalence after adjusting for confounders. More odds for prevalent Hoffa‐synovitis was seen among subjects who engaged in this activity for one day or less per week than who did not perform the activity. No other considerable relationships were noticed. Sensitivity analyses also determined similar outcomes. Therefore, only kneeling shows associations with synovitis.