A prospective, web-based report reveals that noncephalic pain has apparently been germane comorbidity in people suffered from headache or migraine. The cross-sectional modules incorporated in a longitudinal structure was analyzed at baseline and the 3-month to evaluate noncephalic pain sites numbers and 3-month emergence of CM or continual CM.

Out of the total selected interviewees, 769 found to had CM and 8139 had EM, and the prevalence of CM those with EM initially was 3.4%. After adjusting headache-day frequency and demographics, for every added noncephalic pain site at baseline, a 30% increase was noticed in the odds of CM onset amongst those with baseline EM. Further, at  3-month follow-up, in those with baseline CM found with 50.1% persistent CM and following adjusted demographics, CM patients likely to had 15% more persistent CM for every added noncephalic pain site at baseline. These results significantly favour that the noncephalic pain may be considered as an indicator of migraine.