8% L-Arginine and Potassium Nitrate paste: A new hope for sensitive teeth sufferers

According to a novel study published in BMC Oral Health journal, the use of a desensitizing paste containing 8% L-arginine, calcium carbonate, and potassium nitrate was found to effectively reduce tooth sensitivity by sealing dentinal tubules and decreasing dentin permeability. It shows promise in providing immediate and long-term relief for people suffering from dentin hypersensitivity, commonly followed by dental treatments or due to erosive lesions.

Hamideh Sadat Mohammadipour et al. explored the efficacy of this innovative paste through a comprehensive study. Dentin samples from 24-third molars were divided into two groups: one treated with the interventional paste and the other with a placebo. Scanning electron microscopy (SEM) and dentin permeability measurements were used to assess the outcomes. Additionally, a triple-blind, randomized clinical study involving 16 patients assessed the impact of this paste on tooth sensitivity to different stimuli over time.

As evidenced by SEM images, the paste under consideration considerably reduced dentin permeability and effectively occluded dentinal tubules. A marked reduction in sensitivity to cold, touch, and spontaneous stimuli in both groups was observed, with the main group particularly displaying prominent improvement in cold sensitivity 3 months post-treatment.