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Surgery combined with triamcinolone acetonide injection and radiotherapy to treat auricular keloids

Surgery combined with triamcinolone acetonide injection and radiotherapy to treat auricular keloids Surgery combined with triamcinolone acetonide injection and radiotherapy to treat auricular keloids
Surgery combined with triamcinolone acetonide injection and radiotherapy to treat auricular keloids Surgery combined with triamcinolone acetonide injection and radiotherapy to treat auricular keloids

A study was performed to investigate the influence of surgery plus radiotherapy and triamcinolone acetonide injection on auricular keloids.

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Key take away

A combination of individualized surgery and early postsurgery radiotherapy and triamcinolone acetonide injection can effectively treat auricular keloids.

Background

A study was performed to investigate the influence of surgery plus radiotherapy and triamcinolone acetonide injection on auricular keloids.

Method

Overall, 67 patients with 113 auricular keloids were recruited. Based on the particular conditions of lesions, the local tissue, and participants’ wishes, various surgical procedures were chosen for analyzing the scar excision and repairing the defect. Within 24 hours after excision of the keloid, an electron beam irradiation (5 MeV) by the linear accelerator was utilized by radiotherapy with 20 Gy (total dose) at an interval of one day for ten consecutive times.

Triamcinolone acetonide was injected promptly following surgery and per month afterwards in the subsequent three months. Overall, 113 keloids received therapy with a follow-up period of 24 months. For comparing the differences of the 24-month postsurgery Vancouver scar scale (VSS) scores and the presurgery VSS scores, the Wilcoxon matched-pairs rank-sum test was utilized.

Result

In this study, about 12.39% of keloids (n=14) demonstrated subjective recurrence with an 87.61% success rate. Notably, ten keloids scored >10 points (bad outcome), 21 keloids scored 6 to 10 points (fair outcome), and 82 keloids scored <5 points (good outcome) according to the VSS scores. The effective rate was reported to be 91.15%, as shown in Table 1:


Conclusion

A combination of surgery and early postsurgery radiotherapy and triamcinolone acetonide injection is an ideal therapeutic approach to ascertain good auricular appearance, and reduce the incidence of recurrence and complications.

Source:

BMC Surgery

Article:

Individualized surgery combined with radiotherapy and triamcinolone acetonide injection for the treatment of auricular keloids

Authors:

Qiang Sun et al.

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