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Stereotactic body radiotherapy effects for painful non-spine bone metastases treatment

Stereotactic body radiotherapy effects for painful non-spine bone metastases treatment Stereotactic body radiotherapy effects for painful non-spine bone metastases treatment
Stereotactic body radiotherapy effects for painful non-spine bone metastases treatment Stereotactic body radiotherapy effects for painful non-spine bone metastases treatment

A multicentre study was performed to assess the effectiveness of SBRT for painful non-spine bone metastases.

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Key take away

From a recent study, it was found that the stereotactic body radiotherapy (SBRT) for non-spine bone metastases was successful in providing the pain palliation. The results from this study demanded a larger RCT trial to evaluate SBRT in comparison with conventional radiotherapy. 

Background

A multicentre study was performed to assess the effectiveness of SBRT for painful non-spine bone metastases.

Method

In this study, patients suffering from painful non-spine bone metastases were included. They were given a dose of 35 Gy in five parts. The major outcome was the pain response rate calculated six months following the SBRT.

Result

There were 41osseous lesions reported in thirty-eight patients. Patients were suffering mostly from lung cancer. The percentage of sufferers with uterus cancer, prostate cancer and renal cell carcinoma was comparatively less. The bone metastases were mostly found in coxal bones.

The median length of follow-up following the check was eight months. Amongst the lesions, which were able to be evaluated at 3 and 6 months following the SBRT, the pain response rates were 78% and 75%, at 3-month and 6-month correspondingly.

 

Conclusion

SBRT in the treatment of non-spine bone metastases relieved the pain. 

Source:

Practical Radiation Oncology

Article:

Phase II clinical trial of stereotactic body radiotherapy for painful non-spine bone metastases

Authors:

Kei Ito et al.

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