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To evaluate the short-term effects of pneumonia due to SARS-CoV-2 with respect to radiologic/laboratory/clinical indices of risk.
This
prospective follow-up study found short-term clinical effects of COVID-linked
pneumonia to be associated with persistence of symptoms and impaired diffusing
capacity of the lung for carbon monoxide.
To
evaluate the short-term effects of pneumonia due to SARS-CoV-2 with respect to
radiologic/laboratory/clinical indices of risk.
Ninety-four COVID-19 patients were included in this cohort study. These patients had
pneumonia with respiratory failure due to COVID. Overall, 94 patients out of
193 survivors agreed for re-evaluation following hospital discharge after 4
months.
In about 25% of the patients, evidence of pulmonary fibrosis was perceived, as specified by a modified diffusing capacity of the lung for carbon monoxide (DLCO to predict the risk of pulmonary fibrosis); in 6-7% of patients the modification was categorized as of moderate/severe grade.
As per the quality of life assessment via a questionnaire: 52% of the patients
still lamented fatigue, 36% had shortness of breath, 31% insomnia, 21% anxiety
and 10% anorexia nervosa, 14% altered taste. The 3 prognostic indices (Charlson
Comorbidity Index, Brixia radiologic score, and 4C mortality score)
considerably predicted the degree of short-term lung connection.
SARS-CoV-2-related
lung infection is linked to suitable short-term clinical effects, both
concerning the perseverance of symptoms and DLCO impairment; some severity
indices of the disease may forecast the short-term clinical outcome. Future
studies to study its long-term association are needed.
High Blood pressure & Cardiovascular prevention
Short-Term Consequences of SARS-CoV-2-Related Pneumonia: A Follow Up Study
Gianluca E M Boari al.
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