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Safety and efficacy of radiofrequency treatment in knee osteoarthritis

knee.osteoarthritis knee.osteoarthritis
knee.osteoarthritis knee.osteoarthritis

This systematic review and meta-analysis of randomized controlled trials (RCTs) was carried out for comprehensively analyzing safety and efficiency of radiofrequency (RF) to manage knee osteoarthritis.

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Key take away

Radiofrequency is a safe and effective therapy to relieve persistent knee pain and improve knee function in people having osteoarthritis of the knee.

Background

This systematic review and meta-analysis of randomized controlled trials (RCTs) was carried out for comprehensively analyzing safety and efficiency of radiofrequency (RF) to manage knee osteoarthritis.

Method

Several databases such as EMBASE, China National Knowledge Infrastructure, Wanfang Data, PubMed, Cochrane Library, and Web of Science were explored. A total of 15 RCTs with 1009 patients with knee osteoarthritis were incorporated. The reported outcomes in the published RCTs were documented for RF and control groups.

With the aid of Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), Numerical Rating Scale (NRS), Oxford Knee Score (OKS), Global Perceived Effect (GPE) scale, Visual Analogue Scale (VAS), and occurrence of noxious reactions, significant outcomes were comparatively evaluated between both groups.

Result

The RF treatment was found to improve knee function (WOMAC) and pain relief (VAS/NRS score) at 1–2, 4, 12, and 24 weeks post-treatment. With RF therapy, the patients’ degree of satisfaction also improved (GPE scale). No considerable difference was found between group 1 and group 2 in OKS.

No substantial rise in the side effects was reported with RF therapy. The subgroup evaluation of the knee pain at 12 weeks post-treatment signified that the effectiveness of RF therapy aiming the genicular nerve was profoundly superior when compared to intra-articular RF.

Conclusion

To sum up, the use of RF therapy is associated with improvements in knee function (WOMAC score) and pain mitigation (VAS/NRS score).

Source:

Journal of Orthopaedic Surgery and Research

Article:

Efficacy and safety of radiofrequency treatment for improving knee pain and function in knee osteoarthritis: a meta-analysis of randomized controlled trials

Authors:

Jian Liu et al.

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