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Patients with severe COVID infection need hospitalization, which makes them more prone to bacterial and fungal infections. This study aimed to describe the incidence of secondary infections and clinical outcomes in critically ill COVID-19 Indian patients.
A
majority of Gram-negative bacteria in COVID-19 patients were found to be highly
resistant to the higher generation of antimicrobial agents.
Patients
with severe COVID infection need hospitalization, which makes them more prone
to bacterial and fungal infections. This study aimed to describe the incidence
of secondary infections and clinical outcomes in critically ill COVID-19 Indian
patients.
The
presence of secondary infections in hospitalized patients was investigated. The demographic data, infection time following hospital
admission, microbiological and antimicrobial resistance data associated with
secondary infections, and clinical information of COVID-19 patients were
assembled and assessed in this retrospective study,
About 3.6% of patients out of 17,534 hospitalized COVID patients had secondary bacterial or fungal infections. Death among COVID-19 patients due to nosocomial infections was 56.7% compared to the death of 10.6% of patients in total no. of individuals hospitalized.
Gram-negative
bacteria were extracted from 78% of patients, with Klebsiella pneumoniae being
the main pathogen, which was followed by Acinetobacter baumannii (21%).
Polymicrobial infections (plus fungal infections) was reported by 35% of
people. A. Baumannii had high levels of carbapenem resistance (92.6%),
which was followed by K. Pneumoniae (72.8%).
In
hospitalized coronavirus-infected Indian people, there is a low incidence of
bacterial and fungal superinfections. But, the presence of such infections can
lead to serious disease with terrible outcomes since most superinfections are
due to extremely drug-resistant pathogens and are nosocomial. Therefore, to
safeguard patient lives and avoid drug-resistant infections, there is a need
for improving infection control practices and antimicrobial stewardship.
Infection and Drug Resistance
Secondary Infections in Hospitalized COVID-19 Patients: Indian Experience
Sonam Vijay et al.
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