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It is not clear whether individuals with widespread chronic pain (CWP) undergo premature mortality.
Previous studies presented limited evidence for the
occurrence of mortality in patients with chronic widespread pain (CWP). This
study results affirmed that individuals with CWP experience excess mortality.
For which the adverse lifestyle factors may be a culprit. Thus for management
of CWG lifestyle modifications could be adopted.
It is not clear whether individuals with widespread
chronic pain (CWP) undergo premature mortality. This study investigated whether
the correlation exists, also estimated its magnitude and discovered what
factors interfere with the connection.
A cohort analysis was conducted comprising 0.5 million
individuals of 40-69 years old that hired everywhere from Great Britain in
2006-2010. As compared to the individuals without chronic pain, patients with
pain exhibited 'pain all over the body' for >3 months. Data on death (with
cause) was present until mid-2015. To determine a pooled estimate of excess
risk these results along with other published articles were incorporated in a
meta-analysis.
The CWP experienced by a total of seven thousand one
hundred thirty participants with excess mortality. Particular conditions of
death in excess were cancer, respirator,y cardiovascular, and other
disease-associated causes. Excess risk was considerably decreased after
adjustment for high body mass index, low levels of physical activity, smoking, and poor quality diet. All studies
revealed notable excess all-cause, cancer, and cardiovascular mortality.
The individuals with CWP are prone to excess mortality.
UK Biobank outcomes significantly decrease uncertainty around the magnitude of
excess risk and are constant with the excess being defined by adverse lifestyle
factors, which could be targeted during the treatment of such patients.
Ann Rheum Dis. 2017 Jul 21
Persons with chronic widespread pain experience excess mortality: longitudinal results from UK Biobank and meta-analysis.
Macfarlane GJ et al.
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