EN | RU
EN | RU

Help Support

Back

Neurologic indicators in Pediatric Inflammatory Multisystem Syndrome linked with COVID-19

Neurologic indicators in Pediatric Inflammatory Multisystem Syndrome linked with COVID-19 Neurologic indicators in Pediatric Inflammatory Multisystem Syndrome linked with COVID-19
Neurologic indicators in Pediatric Inflammatory Multisystem Syndrome linked with COVID-19 Neurologic indicators in Pediatric Inflammatory Multisystem Syndrome linked with COVID-19

This study aimed to describe the neurologic features in PIMS-TS.

See All

Key take away

In the quest to find neurologic symptoms in pediatric inflammatory multisystem syndrome temporally linked with SARS-CoV-2 (PIMS-TS), the children with neurologic symptoms had notably higher markers of systemic inflammation, as revealed from this single-center retrospective observational study. 

Background

This study aimed to describe the neurologic features in PIMS-TS.

Method

A total of 75 children (mean age of 7.9 years) with PIMS-TS were identified. A retrospective review was perfomed to assess the clinical and investigative characteristics together with short-term consequences of children with neurologic symptoms.

Result

Nine children (12%) were found to have neurologic presentations as shown below:

Cranial images abnormalities was observed in 4 children. After 3 months, 4 children had complete recovery, 1 had unilateral paresis, 3 had behavioral changes, and 1 child deceased. Children with neurologic connection had greater systemic inflammatory and prothrombotic markers. These markers were greater in those who did not completely recover at 3 months.

Similar risk factors for PIMS-TS was observed in children with and no neurologic connection.

Conclusion

About 12% patients with PIMS-TS displayed wide neurologic characteristics. Half of these children had full recovery with no neurologic damage at 3 months. Children with neurologic connection and in those who did not recover fully had considerably greater systemic inflammatory markers.

Source:

Neurology(R) neuroimmunology & neuroinflammation

Article:

Systemic Inflammation Is Associated With Neurologic Involvement in Pediatric Inflammatory Multisystem Syndrome Associated With SARS-CoV-2

Authors:

Mario Sa et al.

Comments (0)

You want to delete this comment? Please mention comment Invalid Text Content Text Content cannot me more than 1000 Something Went Wrong Cancel Confirm Confirm Delete Hide Replies View Replies View Replies en ru ua
Try: