EN | RU
EN | RU

Help Support

Back

Long-term impact of lipid-based nutrient supplements on child growth

lipid-based nutrient supplements lipid-based nutrient supplements
lipid-based nutrient supplements lipid-based nutrient supplements

This randomized controlled trial examined how small-quantity lipid-based nutrient supplements (SQ-LNS) during pregnancy, postpartum and infancy affect child growth and blood pressure at 9 to 11 years in the International Lipid-Based Nutrient Supplements (iLiNS)-DYAD-Ghana cohort.

See All

Key take away

Supplementation of lipid-based nutrient supplements during the significant 1000-day period, including the prenatal phase and the first 2 years after birth, aids long-term linear growth in girls and children of healthy-weight mothers.

Background

This randomized controlled trial examined how small-quantity lipid-based nutrient supplements (SQ-LNS) during pregnancy, postpartum and infancy affect child growth and blood pressure at 9 to 11 years in the International Lipid-Based Nutrient Supplements (iLiNS)-DYAD-Ghana cohort.

Method

One-thousand three-hundred twenty females (less than or equal to 20 weeks of pregnancy) were randomly allocated to receive every day:

  • Iron and folic acid during gestation and placebo during 6 months postpartum or multiple micronutrients during pregnancy and 6 months postpartum
  • SQ-LNS during pregnancy and 6-months after child birth and for their children aged in the age group of 6-18 months

Nine-hundred sixty-six children (aged 9-11 years) were re-enrolled. Parameters such as arm circumference, height-for-age z-score (HAZ), triceps skin-fold thickness, body mass index (BMI) for-age z-score, waist-to-height ratio, and blood pressure were noted. A comparison between the SQ-LNS and control groups (iron and folic acid + multiple micronutrients) was done while accounting for the child's age.

Result

The average (standard deviation [SD]) HAZ in the SQ-LNS group was -0.04 (0.96) and was -0.16 (0.99) in the control group, with a p-value of 0.060. No considerable group differences were detected in other outcomes (p > 0.10). However, the effects of HAZ varied depending on the child's sex and pre-pregnancy BMI. As observed in women, HAZ was higher in the SQ-LNS group when compared to the control group; in males, it did not differ (Table 1):

Among children of females with a BMI of less than 25, HAZ was higher in the SQ-LNS compared to the control group; among females with a BMI of more than equal to 25, these parameters did not vary (Table 2):

Conclusion

The continued benefits of prenatal and postnatal SQ-LNS are apparent in the continued linear growth of girls and children born to mothers with normal weight. Greater body height in women could most likely reduce small-for-gestational-age childbirths and related complications.

Source:

The American Journal of Clinical Nutrition

Article:

Sustained effects of small-quantity lipid-based nutrient supplements provided during the first 1000 days on child growth at 9–11 y in a randomized controlled trial in Ghana

Authors:

Helena J Bentil et al.

Comments (0)

You want to delete this comment? Please mention comment Invalid Text Content Text Content cannot me more than 1000 Something Went Wrong Cancel Confirm Confirm Delete Hide Replies View Replies View Replies en ru ua
Try: