Categories
Change Password!
Reset Password!
To examine the influence of additional intravenous Acetaminophen to manage pain appear after the total joint arthroplasty (TJA).
Pain control after the major orthopedic surgery has become a serious
clinical problem. Although numerous analgesic methods have been applied, they
have not provided sufficient relief from the pain. Therefore Liqing Yang et
al performed a meta-analysis and reported that intravenous acetaminophen to
multimodal analgesia could significantly reduce pain.
To examine the influence of additional intravenous
Acetaminophen to manage pain appear after the total joint arthroplasty (TJA).
PubMed, ScienceDirect, the Cochrane Library, Medline, and
Embase was searched and selected randomised controlled trials (RCTs) and
non-RCTs. The quality evaluations were conducted as per the Cochrane systematic
review method. Opioid consumption and postoperative pain scores were taken as
the primary endpoints. Stata 11.0 software was used to perform the meta-analysis.
Four studies comprising 865 participants were selected
for the analysis. The meta-analysis revealed significant differences between
groups regarding pain scores and opioid consumption at POD 1, POD 2, and POD 3.
Additional intravenous Acetaminophen to multimodal
analgesia could considerably lessen the pain and opioid intake following total
joint arthroplasty with fewer adverse events. Greater quality RCTs are needed
for more research.
Int J Surg. 2017 Sep 14
Intravenous acetaminophen as an adjunct to multimodal analgesia after total knee and hip arthroplasty: A systematic review and meta-analysis
Liqing Yang et al.
Comments (0)