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A randomized controlled trial was carried to assess the efficacy of epidural injection on spine mobility, pain, disease activity, and the activity of everyday living in individuals having spondyloarthritis with limited spine mobility.
The caudal epidural injection of
triamcinolone and lidocaine is a practical and cost-effective approach for
alleviating pain and improves the functioning of the spine and disease activity
scores in individuals suffering from axial spondyloarthritis.
A randomized controlled trial was
carried to assess the efficacy of epidural injection on spine mobility, pain,
disease activity, and the activity of everyday living in individuals having
spondyloarthritis with limited spine mobility.
The study cohort included 47 axial spondyloarthritis patients. Individuals were allocated into two arms: (I) Group A was administered caudal epidural injections, ultrasound-guided, with 1% lidocaine hydrochloride mixed with triamcinolone (ii) Group B was not given any injections. All the subjects fulfilled the Assessment of Spondyloarthritis International Society (ASAS) criteria for axial spondyloarthritis.
The outcome parameters were: (i)
visual analogue scale, (ii) lateral lumbar flexion, (iii) modified Schober
test, (iv) Oswestry disability index (ODI), and (v) Ankylosing Spondylitis
Disease Activity Score (ASDAS) with an evaluation at baseline, two and eight
weeks after therapy.
A substantial difference was noted between both the groups
regarding spine mobility, pain, ODI, and ASDAS scores in favor of group A. This
impact was at its maximum after two weeks. Despite the decrease in this effect
after two months, the difference between the arms remained substantial. Young
age, elevated disease activity, and a shorter duration of disease were linked
with improved outcomes.
The epidural injection of
triamcinolone and lidocaine is beneficial to treat axial spondyloarthritis
patients with relatively sustained effects and acceptable complications.
The Korean Journal of Pain
Ultrasound-guided epidural block in axial spondyloarthritis patients with limited spine mobility: a randomized controlled trial
AM Elsaman et al.
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