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To study the effect of Vitamin B2 on the duration, incidence, and pain associated with migraine.
Migraine is a commonly reported neurological
condition that leads to debilitating headaches. Studies have shown the
association of Vitamin B2 deficiency with migraine. As per this systematic
review and meta-analysis, the use of Vitamin B2 400 mg was found to be
effective for migraine.
To study the effect of Vitamin B2 on the
duration, incidence, and pain associated with migraine.
The Preferred Reporting Items for Systematic
reviews and Meta-Analyses (PRISMA) guideline was used
for the studying practice. PubMed, Embase, Cochrane, CINAHL, and CEPS were
explored with the search terms being migraine, Vitamin B2, and prophylactic.
Overall 9 articles were considered for systemic
review and meta-analysis. Also, 8 randomized controlled trials and 1 controlled
clinical trial with 673 migraine patients were studied via meta-analysis. A
significant decrease in days of the migraine, duration, incidence, and pain score
was found in patients using Vitamin B2.
As per the pooled analysis of available
randomized controlled clinical trials, Vitamin B2 400 mg supplementation when
used daily for 3 months had a noteworthy effect on days, duration, incidence,
and pain reduction due to migraine.
Nutritional Neuroscience
Effect of Vitamin B2 supplementation on migraine prophylaxis: a systematic review and meta-analysis
Yu-Shiue Chen et al.
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