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Arthrocen supplementation may alleviate joint pain and dysfunctionality in osteoarthritis patients

Osteoarthritis Osteoarthritis
Osteoarthritis Osteoarthritis

This randomized, placebo-controlled, double-blind clinical trial investigated the efficacy and effects of arthrocen treatment on cytokine changes in people having osteoarthritis of the knee.

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Key take away

In people diagnosed with mild to moderate osteoarthritis, arthrocen may improve the patient's quality of life by reducing joint pain and inflammation, and enhancing functional activities.

Background

This randomized, placebo-controlled, double-blind clinical trial investigated the efficacy and effects of arthrocen treatment on cytokine changes in people having osteoarthritis of the knee.

Method

Participants were randomly segregated to get either 300 mg/day arthrocen (n = 61) or placebo (n = 58) for three months. Collection of data was done utilizing questionnaires including Lequesne index of severity for osteoarthritis of the knee (LISOK), the Western Ontario and McMaster Universities osteoarthritis index (WOMAC), 20-item short form survey (SF-20), and visual analog scale (VAS) as pain quality indices.

With the aid of an ELISA reader, the serum levels of interleukins 2 (IL-2), IL-17α, IL-10, IL-4, and tumor necrosis factor-alpha were estimated.

Result

Participants were randomly segregated to get either 300 mg/day arthrocen (n = 61) or placebo (n = 58) for three months. Collection of data was done utilizing questionnaires including Lequesne index of severity for osteoarthritis of the knee (LISOK), the Western Ontario and McMaster Universities osteoarthritis index (WOMAC), 20-item short form survey (SF-20), and visual analog scale (VAS) as pain quality indices.

With the aid of an ELISA reader, the serum levels of interleukins 2 (IL-2), IL-17α, IL-10, IL-4, and tumor necrosis factor-alpha were estimated.

Conclusion

Arthrocen (avocado/soy unsaponifiables) supplementation may lead to remarkable improvements in  quality of life, activities of daily living, and pain without eliciting any adverse effects in the long term.

Source:

Medicina (Kaunas)

Article:

Joint Dysfunctionality Alleviation along with Systemic Inflammation Reduction Following Arthrocen Treatment in Patients with Knee Osteoarthritis: A Randomized Double-Blind Placebo-Controlled Clinical Trial

Authors:

Ramin Goudarzi et al.

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