EN | RU
EN | RU

Help Support

Back

Vitamin C supplementation may reduce gout risk among middle-aged clinicians

vitamin C for Gout vitamin C for Gout
vitamin C for Gout vitamin C for Gout

What's new?

Use of vitamin C among middle-aged medical practitioners was associated with 12% decreased risk of new gout diagnoses.

A post-hoc analysis depicted that supplemental vitamin C moderately lowers new gout diagnoses risk among middle-aged male clinicians. Stephen P Juraschek et al. aimed to assess the impact of supplemental vitamin E  (400 IU every other day, pre-specified secondary exposure) and vitamin C (500 mg/day, pre-specified primary exposure) on gout diagnoses. An assessment of data was conducted from Physicians’ Health Study II, a randomized trial of vitamin C and vitamin E.

A total of 14,641 male physicians with a mean age of 64 years were randomized and 6.5% were suffering from gout before randomization. New gout diagnoses, self-indicated at baseline and during the follow-up period of up to ten years were the major endpoint ascertained. During follow-up, the rate of occurrence of new gout diagnosis among those given vitamin C and placebo, is shown in Table 1:

Vitamin C supplementation decreased novel gout diagnoses by 12% (Hazard ratio [HR]: 0.88). These impacts were highest among those with a body mass index of  <25 kg/m2. No correlation was found between vitamin E and new gout diagnosis (HR: 1.05). Hence, vitamin C administration appears to be valuable to minimize the risk of novel gout diagnoses. 

Source:

The American Journal of Clinical Nutrition

Article:

Effects of vitamin C supplementation on gout risk: results from the physicians’ health study II trial

Authors:

Stephen P Juraschek et al.

Comments (0)

You want to delete this comment? Please mention comment Invalid Text Content Text Content cannot me more than 1000 Something Went Wrong Cancel Confirm Confirm Delete Hide Replies View Replies View Replies en ru
Try: