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Magnesium sulfate (MgSO4) was found
to be associated with pain relief after cesarean section.
As per the outcomes of
a recent meta-analysis, magnesium sulfate was useful in lowering the highest visual analog scale (VAS) in women who undertook general anesthesia,
spinal anesthesia, or epidural for cesarean section. It also helped in significantly
decreasing the postsurgical pain after cesarean section.
Siguang Ma and investigators reviewed the
effectiveness of MgSO4 on improving postsurgical analgesia following
cesarean section. The Cochrane library, PubMed, and Embase were explored for
the relevant randomized controlled trials.
Overall, 880 women were considered (440 in the
MgSO4 group and 440 in the control group). MgSO4 had a
statistically noteworthy effect than the control group concerning the highest
VAS and the last VAS. Patients in the MgSO4 group had prolonged the
time to the initial analgesia usage (standardized mean difference [SMD] = −3.03 min) and lowered
analgesia consumption (SMD = −3.20 mg of IV morphine equivalent) than the patients
in the control group.
PAIN Practice
Magnesium sulfate reduces postoperative pain in women with cesarean section: a meta‐analysis of randomized controlled trials
Siguang Ma et al.
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