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The topical application of Isoconazole
nitrate cream can be an effective option to manage pain and itching due to
otomycosis.
A novel prospective study published in the American Journal
of Otolaryngology found Isoconazole nitrate cream to be an effective and easily
applicable azole antifungal drug for otomycosis treatment.
The efficacy of topical isoconazole nitrate 1% cream in the
treatment of otomycosis was investigated in 43 patients suffering from with
itching, ear pain, sensation of
ear fullness, and
hearing loss. These patients were identified with unilateral otomycosis. The
external ear canal was filled with isoconazole nitrate 1% cream following the
process of aspiration and cleaning. The control assessments were accomplished
on the 5, 10, 15, and 20 days of the treatment. The patients were asked about
how many days the pain and itching entirely relieved following the use of the
cream. Thereafter, the answers were noted.
Complete recovery was observed concerning pain and otoendoscopic findings in the initial control assessment of 23 out of 25 patients suffering from pain. In the secondary control assessment, a complete recovery of the remaining 2 patients was observed (100%, 25 patients). In a total of 35 patients with itching, the itching and otoendoscopic findings improved completely in different control examinations as shown in the following table:
The use of Isoconazole nitrate,
tropically can be beneficial in patients suffering from fungal ear infection.
American Journal of Otolaryngology
Efficacy of topical isoconazole nitrate in the treatment of otomycosis
Filiz Gülüstan et al.
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