EN | RU
EN | RU

Help Support

Back

PRP and Platelet-related products improve pain scores in patients with radicular pain

Radiculopathy Radiculopathy
Radiculopathy Radiculopathy

What's new?

Epidural injections containing PRP or platelet-derived products are effective and safe for the treatment of radicular pain.

According to a systematic review, epidural injection with plasma rich in growth factors (PRGF), platelet lysate (PL), or platelet rich plasma (PRP) is associated with pain reduction in patients with radicular pain. Eva Kubrova et al. sought to assess the efficacy of epidural steroid injections incorporating PRP or related products for the relief of radicular pain.

Databases such as Google Scholar, Cochrane Central Register of Controlled Trials (CENTRAL), Embase and MEDLINE/PubMed were explored. Overall, 9 observational studies and 3 randomized controlled trials were among the twelve studies that were incorporated in the qualitative analysis. Pain intensity was the major endpoint, while adverse events, structural alterations on advanced imaging, and functional advancement were the secondary outcomes ascertained.

Following PRP, PRGF, or PL epidural injection, better pain severity and functional results were witnessed. When compared to the group getting epidural steroid injections, the PRP cohort showed longer-lasting or comparable pain alleviation, with benefits lasting up to 12 to 24 months. Due to the risk of bias, indirectness, and imprecision, the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) assessment revealed a very-low evidence certainty. To sum up, PRP and platelet-related products are valuable for the treatment of radiculopathy.

Source:

Biomedicines

Article:

Platelet Rich Plasma and Platelet-Related Products in the Treatment of Radiculopathy—A Systematic Review of the Literature

Authors:

Eva Kubrova et al.

Comments (0)

You want to delete this comment? Please mention comment Invalid Text Content Text Content cannot me more than 1000 Something Went Wrong Cancel Confirm Confirm Delete Hide Replies View Replies View Replies en ru ua
Try: