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Platelet-rich fibrin
can be an effective, inexpensive technique and
used as a substitute for other kinds of nasal tampons following the Endoscopic sinus surgery.
According to a prospective study published in
the American Journal of Otolaryngology, the use of platelet-rich fibrin (PRF)
lead to improved outcomes concerning tissue
healing, adhesion formation, infection, bleeding, granulation, and frontal
ostium stenosis following the Endoscopic sinus surgery (ESS).
ESS is a
well-recognized procedure for nasal polyps and refractory chronic
rhinosinusitis. Good wound healing and less adhesion formation is pivotal for
preventing revision surgery. PRF has been known promote tissue healing in
dental implant and plastic surgery.
Hüseyin Sari et al. recruited 50 patients who underwent ESS
for nasal polyposis diagnosis. In one nasal cavity, the middle meatus was
packed with PRF and reinforced with nasal dressing, whereas in the other nasal
cavity middle meatus had only nasal dressing. After the surgery, the patients
were followed up at 1st, 2nd, 3rd, 4th, 8th, and 12th week. The occurrence of adhesion, crusting,
bleeding, frontal ostium stenosis, granulation, and infection were determined
and if available, the grading of these complications was done via a
questionnaire.
As found, the above mentioned
complications were less common in the PRF group, and there was a
statistically significant difference amongst the groups.
American Journal of Otolaryngology
The effect of platelet-rich fibrin (PRF) on wound healing, adhesion, and hemostasis after endoscopic sinus surgery in patients with nasal polyposis
HüseyinSari et al.
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