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A double-blind, randomized, placebo-controlled study was performed to investigate the impact of vitamin D intake on metabolic profiles and clinical symptoms in individuals suffering from endometriosis.
Administration of vitamin D in
individuals having endometriosis led to significant improvement of pelvic pain,
high-sensitivity C-reactive protein, total-/HDL-cholesterol ratio, and total
antioxidant capacity levels. However, the metabolic profiles and other clinical
symptoms were not affected.
A
double-blind, randomized, placebo-controlled study was performed to investigate
the impact of vitamin D intake on metabolic profiles and clinical symptoms in
individuals suffering from endometriosis.
About 60 participants
(age 18-40 years) suffering from endometriosis were recruited. Individuals were
randomized to receive either a 50,000 IU vitamin D group (n=30) or placebo
group (n=30) each two weeks for 12 weeks.
Supplementing vitamin D substantially decreased
pelvic pain (β - 1.12) and total-/HDL-cholesterol ratio (β - 0.29) when
compared to the placebo-recipients. Furthermore, vitamin D consumption led to a
considerable decline in high-sensitivity C-reactive protein (β - 0.64 mg/L) and
a considerable rise in total antioxidant capacity (β - 47.54 mmol/L) compared
with the placebo.
Vitamin D intake effectively
relieves pelvic pain in endometriosis patients.
Gynecological Endocrinology
The effect of vitamin D supplementation on clinical symptoms and metabolic profiles in patients with endometriosis
Abolfazl Mehdizadehkashi et al.
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