Categories
Change Password!
Reset Password!
This randomised double-blind study aimed to evaluate the efficacy of sodium thiopental-fentanyl (TF) with ketamine-propofol (KP) for procedural sedation and analgesia in the emergency department.
In this study, strong muscle relaxation of sodium thiopental and very brief sedative
effects of this medication was the positive hypotheses to compare this medicine
with ketofol. Although both combinations of KP and TF were found effective with
no noteworthy complication. But, sodium thiopental offered more desirable
post-sedation analgesia, reduced agitation and very transitory sedative
effects.
This randomised double-blind study aimed to
evaluate the efficacy of sodium thiopental-fentanyl (TF) with ketamine-propofol
(KP) for procedural sedation and analgesia in the emergency department.
The patients were
subjected to receive either KP (47 patients) or TF (49 patients) for desired
sedation level. A comparison of respiratory and haemodynamic issues, recovery
agitation, patient and physician satisfaction, recall of painful procedure,
nausea and vomiting were done.
The mean and SD scores patients' and physicians’ satisfaction performing the procedures in TF and KP groups were almost similar. Patient recalled was detected in 39 (79.59%) and 18 (38.29%) of patients in the TF and KP groups, respectively. About 2.1% and 8.1% in the KP and TF groups reported transient hypoxia.
It lead to 4.2% versus 8.1% airway manoeuvres being accomplished in KP and TF groups, without the requirement for endotracheal intubation or additional admission. A detail of the results has been mentioned in the following Table 1:
Table 1: Efficacy and adverse
effects of Sodium thiopental–fentanyl and Ketamine–propofol groups
Emergency Medicine Journal: EMJ
Comparison of the efficacy of ketamine- propofol versus sodium thiopental-fentanyl in sedation: a randomised clinical trial
Maryam Bahreini et al.
Comments (0)