Migraine is the most common health concern associated with comorbidities and subjective cognitive decline (SCD) but there are limited evidences that explains the association of SCD with migraine. In this study, a significant prevalence of cognitive decline has been estimated in migraine patients and a correlation has been found between comorbidities of migraine like depression and short sleep and SCD.

Migraine is the most common health concern associated with comorbidities and subjective cognitive decline (SCD) but there are limited evidences that explains the association of SCD with migraine. In this study, a significant prevalence of cognitive decline has been estimated in migraine patients and a correlation has been found between comorbidities of migraine like depression and short sleep and SCD.

The patients who achieved in the normal range of the Korean-Montreal Cognitive  Assessment and Korean-Mini Mental State Examination. Subjects with ≥7 were allotted to the SCD group. Both the groups analysed using Generalized Anxiety Disorder-7, Pittsburgh Sleep Quality Index, Headache Impact Test-6, and Patient Health Questionnaire-9.

One hundred and eighty-eight patients were selected for the analysis. A total of 44.7% recognized having SCD with 6.5 ± 5.5 mean Subjective Cognitive Decline Questionnaire (SCD-Q) score. Higher headache impact and pain intensity, the incidence of depression, anxiety with shorter sleep duration and reduced sleep quality were seen in the migraineurs with SCD during weekdays than migraineurs without SCD. Groups exhibited no difference regarding migraine type, sleep duration, medication, sex, or age. Adjusting for sex, age, psychological variables, and headache features, depression showed a relationship with raised risk of SCD and sleep duration during weekdays was related to reduced risk of SCD.

A non-negligible number of individuals with migraine presented SCD. Short sleep duration and depression during weekdays were associated with SCD amongst adult migraineurs.