In coronavirus-infected subjects, the usage of fluticasone nasal spray and triamcinolone paste considerably enhanced olfactory and taste functions respectively. For all anosmia and dysgeusia cases, the recovery of smell senses and the taste occurred within a week. 

A prospective interventional study was performed to investigate the efficacy of fluticasone nasal sprays in odour disorders and triamcinolone oral paste in taste dysfunction in individuals having laboratory-confirmed coronavirus disease 2019 (COVID-19).

In total, 120 patients diagnosed with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (mean age 50.88 ± 15.93 years) were recruited. The control group (mean age is 51.2 ± 14.89) did not receive any interventional therapy and only supervision of the symptoms was carried out to evaluate the recovery time. Testing was done on days one and five after proven infection by reverse transcription-polymerase chain reaction test.

Following the usage of triamcinolone in the mouth and fluticasone in the nose, substantial improvements were noted in identifying all the smell and taste on day five in comparison with day one in the case-cohort. During the comparison of smell and taste of cases vs. the control group, either no improvement or deterioration in taste or smell on day five in the control group was noted.

Using fluticasone nasal spray and triamcinolone paste improves olfactory and taste functions respectively in coronavirus-infected patients.