This observational study aimed to comprehend the significance of hypermobility to symptoms in fibromyalgia and CFS/ME.
Symptomatic joint
hypermobility and variants of connective tissue disorder were found to
influence fibromyalgia and chronic fatigue syndrome/ myalgic encephalomyelitis
(CFS/ME)
This observational study aimed to comprehend the
significance of hypermobility to symptoms in fibromyalgia and CFS/ME.
The study included 63 patients with a confirmed
diagnosis of fibromyalgia and/or CFS/ME
and 24 healthy individuals as controls. Symptomatic hypermobility was
evaluated.
From a research perspective, fibromyalgia and
CFS/ME are almost indistinguishable as considerable overlap was witnessed in
patients of fibromyalgia and CFS/ME. About 81% of patients fulfilled the
Brighton criteria for hypermobility syndrome (odds ratio 7.08) and 18%
fulfilled the 2017 hypermobile Ehlers–Danlos syndrome standards. Symptom levels
were significantly predicted via the hypermobility scores.
Symptomatic hypermobility is mainly pertinent to
fibromyalgia and CFS/ME, and the results indicate high rates of underdiagnosis.
These poorly understood disorders negatively affect the quality of life in
people suffering from these conditions.
Clinical Medicine
Beyond bones: The relevance of variants of connective tissue (hypermobility) to fibromyalgia, ME/CFS and controversies surrounding diagnostic classification: an observational study
Jessica A Eccles et al.
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