Role of obesity in catheter-associated bloodstream infections

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Created On: 07/01/2023

For summarizing the existing evidences on the connection between obesity and bloodstream infections risk, a systematic review and meta-analysis was carried out.

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Key take away

Overweight, obesity and severe obesity are significantly linked with a greater risk of catheter-associated bloodstream infections.

Background

For summarizing the existing evidences on the connection between obesity and bloodstream infections risk, a systematic review and meta-analysis was carried out.

Method

Databases like PubMed, Web of Science, EMBASE, and MEDLINE were searched for the relevant studies published before January 2022. Utilizing a random-effects model, a meta-analysis was carried out.

Result

In total, 5 articles were incorporated. Volunteers with body mass index ≥ 25 kg/m2 had an elevated risk of catheter-linked bloodstream infection (Odds Ratio [OR] 1.75) in the overall analysis. Additional studies revealed that people with overweight, obesity and severe obesity were more susceptible to develop catheter-connected bloodstream infections (OR 1.51 [1.10–2.08], OR 1.43 [1.12–1.82] and OR 2.74 [1.85–4.05], respectively).

Conclusion

There is a close connection between obesity and a higher risk of bloodstream infections linked with catheter use. In clinical work, it is crucial to pay close attention to the risks and prognosis of obese people undergoing vascular catheterization.