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This research focused to examine the treatment outcomes of following two-stage knee reimplantation and classify the risk factors for uncontrolled PJI of knees.
Periprosthetic infection (PJI) following TKA poses as a
serious problem, and doctors should recognize the associated risk factors to prevent
its relapse. This present study found that 17
out of 70 patients developed recurrent infections after reimplantation; with
wound issues, fungal species, etc. as risk determinants/factors for the same. This can help in advising patients and physicians for a better
understanding and taking caution in PJI treatment.
This research focused to examine the
treatment outcomes of following two-stage knee reimplantation and classify the
risk factors for uncontrolled PJI of knees.
All in all, seventy knees diagnosed with a PJI treated with
two-stage reimplantation were retrospectively reviewed. Following
reimplantation, the patients in group C i.e. controlled infection group needed
no further medication or surgical treatment in 2 years. Group U patients i.e.
uncontrolled infection group portrayed symptoms of active infection following the
resection arthroplasty or were again infected after 2-stage reimplantation. A
comparison of group C and group U was done and potential risk factors for
uncontrolled PJI were investigated.
At follow-up, 53 (75.7%) knees were
clinically considered free from infection at the latest follow-up. The rest 17
knees (24.3%) needed extra surgical procedures after the 2-stage
reimplantation. No statistically significant difference was found between the
groups, considering the demographics. Group U had statistically more common
wound issues (p = 0.030). Between groups C and U, pre-reimplantation
C-reactive protein (CRP) was statistically different (0.44 and 1.70, p = 0.025).
Fungus species was statistically more prevalent in group U than group C (p = 0.031).
In the included cases, the reinfection rate
of our two-stage reimplantation protocol was 24.3%. Group U had statistically
more common wound complications, higher pre-reimplantation CRP levels, and
fungus species were than with group C.
Knee Surgery & Related Research
Risk factors of uncontrolled periprosthetic knee joint infection after two-stage reimplantation
Du-Han Kim et al.
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