The stomach plays a key role in the digestion of food and has conventionally been seen as a muscular sac responsible for starting the second phase of digestion. However, this oversimplified perspective disregards its intricate role as a highly advanced endocrine organ, possessing distinct characteristics in terms of microbiology, immunology, biochemistry, and physiology. All ingested materials, including our nutritional intake, must first navigate through the complexities of the stomach.