Nasal packing materials play a crucial role in endoscopic sinus surgery by promoting hemostasis and aiding in wound healing. Using a nasal pack following surgery improves wound healing and positively impacts patient-reported outcomes.

The objective of this comprehensive systematic review without meta-analysis, known as synthesis without meta-analysis (SwiM), was to evaluate the effectiveness of functional biomaterials following endoscopic sinus surgery.

The researchers conducted a systematic search using pre-established criteria to determine which articles to include and exclude. A total of 31 relevant articles were found by searching databases such as PubMed, Scopus, and Web of Science. 

Using the Cochrane risk-of-bias tool for randomized trials (RoB 2), the evaluation of the potential bias in each study was done. Following SWiM guidelines, the studies were thoroughly examined, and their biomaterial types and functional properties were carefully categorized.

Despite variations among the studies, chitosan, gelatin, hyaluronic acid, and starch-based materials demonstrated improved endoscopic scores and promising potential as nasal packing materials.

The application of a nasal pack following endoscopic sinus surgery maximizes postoperative recovery.