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To study the effectiveness of daily use of proton pump inhibitor - omeprazole 40 mg and 20 mg using PROMs in cases of heartburn due to non-erosive reflux disease, GERD, stomach inflammation, indigestion, functional heartburn, peptic ulcers.
Heartburn or acid reflux mainly affect the upper
gastrointestinal tract and is linked with gastroesophageal reflux disease
(GERD) and gastritis. This multi-country, multi-center observational study
comprising of 18,724 patients emphasized omeprazole 40 mg as the preferred
therapy for improving patient-reported outcome measures (PROMs) and quality of
life in heartburn-related disorders.
To study the effectiveness of daily use of
proton pump inhibitor - omeprazole 40 mg and 20 mg using PROMs in cases of
heartburn due to non-erosive reflux disease, GERD, stomach inflammation, indigestion, functional heartburn,
peptic ulcers.
Overall, 18,724 patients with heartburn (GERD;10,509 patients having gastritis) were prescribed omeprazole (Dr. Reddy’s omeprazole [DO]/generic omeprazole [GO]/branded omeprazole [BO]) 40 mg (as a total daily dose) and 20 mg.
Noteworthy improvement with omeprazole 40 mg
compared to 20 mg in SF-LDQ, the relief obtained via medicine in heartburn
patients as per the statistical comparative analysis. In the ‘a lot’ and
‘complete’ relief group, DO 20 mg had a greater improvement.
Total omeprazole dose of 40 mg on a routine
basis portrayed improved efficacy than omeprazole 20 mg concerning PROM in
heartburn patients.
International Journal of Research in Medical Sciences
Effect of omeprazole on patient-reported outcome measures in uninvestigated heartburn: a multi-country, multi-center observational study
Leonid B. Lazebnik et al.
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