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To study the effectiveness of multi-ingredient supplement with a specific Myo-Inositol to D-Chiro-Inositol (3.6:1, MYO: DCI), along with antioxidants, vitamins and minerals in women undergoing in vitro fertilization (IVF) and with a history of failed assisted reproductive technique (ART).
Supplementation prior to fertility treatment with a precise ratio of Myo-Inositol, D-Chiro-Inositol, antioxidants, minerals and vitamins may benefit sub-fertile women (average age=35 years) with poor ART prognostic factors (weakened ovarian reserve, endocrine changes and/or compromised quality of oocyte).
To study the effectiveness of multi-ingredient supplement with a specific Myo-Inositol to D-Chiro-Inositol (3.6:1, MYO: DCI), along with antioxidants, vitamins and minerals in women undergoing in vitro fertilization (IVF) and with a history of failed assisted reproductive technique (ART).
This preliminary evidence of the case series comprises 5 women (average age=34.8 years). They had a history of infertility and previously failed ART. These women were supplemented with inositol supplement under consideration for 1-3 months prior to IVF.
Among the 5 women featured in this series, 4 had a PCOS diagnosis (Cases 1, 3-5), while 1 exhibited diminished ovarian reserve (Case 2). Specifically, 3 patients had undergone 2 failed IVF cycles, 1 patient had 3 failed IVF attempts, and 1 patient had 4 failed intrauterine inseminations. As found, all participants experienced positive outcomes in ART following supplementation for 1 to 3 months before ovarian puncture. Notably, each had previously undergone unsuccessful ART attempts.
This series of case studies provides preliminary evidence that supports the use of this multi-nutritional supplementation to positively contribute to female fertility in women undergoing IVF, with a history of infertility and earlier unsuccessful ART.
Sage Journals: Clinical Medicine Insights: Case Reports
Treatment With a Patented 3.6:1 Myo-Inositol to D-chiro-Inositol Ratio, Antioxidants, Vitamins and Minerals Food Supplement in Women With a History of Assisted Reproductive Technique (ART) Failures: A Series of Case Reports
A. Armijo-Sánchez et al.
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