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To compare the efficacy of GNB via classical anatomical targets (CT) contrasted with the revised targets (RT) in knee osteoarthritis pain.
The Genicular Nerve Blockade (GNB) is used to
obstruct the nerve signals in
the knee for a short period. This randomized controlled trial supported the use
of revised targets for GNB for effective pain relief and improved joint
function.
To compare the efficacy of GNB via classical
anatomical targets (CT) contrasted with the revised targets (RT) in knee osteoarthritis
pain.
Fifty-five patients with chronic knee
osteoarthritis pain were administered with a GNB (via lidocaine 1% 2 mL plus
triamcinolone 20 mg). These patients were divided into 2 groups based on the
type of target used i.e CT-group or classical targets (28 patients) and
RT-group or revised targets (27 patients).
At the starting point, and 1 hour, 1 day, 1 week, 4 weeks, and 12 weeks, the
different health assessment tools [Western Ontario and McMaster Universities
osteoarthritis index score (WOMAC), Numeric rating pain scale (NRS),
Quantitative analgesic questionnaire, Oxford knee score] were used to evaluate
pain, analgesic use, and physical function.
Greater NRS mean score reduction at 1 hour was
observed in the RT group. Also, the patients in the RT group had more than 50%
knee pain decrease with statistically significant only after 1 hour (82.1%
versus 100%). Till 12 weeks, both the groups had significant pain relief and
joint function recovery.
At 1 hour, the RT group had more pain relief and
a greater percentage of effective responders was observed. The sizable volume
of therapeutic GNB administered could have balanced the absence of accuracy of
the CT, lessening differences in outcomes between both the targets.
Pain Medicine
A Comparison of Genicular Nerve Blockade With Corticosteroids Using Either Classical Anatomical Targets vs Revised Targets for Pain and Function in Knee Osteoarthritis: A Double-Blind, Randomized Controlled Trial
Loïc Fonkoue et al.
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