Dextrose versus Ringer's lactate solution for nausea and vomiting prevention after laparoscopic cholecystectomy

The administration of fluid supplementation with intravenous 5% Dextrose before the elective laparoscopic cholecystectomy significantly reduces nausea and vomiting after the surgery.

To evaluate how effective intraoperative Dextrose 5% intravenous (IV) is compared to Ringer's lactate solution IV in preventing post-surgical nausea and vomiting in adults undergoing elective laparoscopic cholecystectomy.

The patient data was prospectively collected after obtaining verbal consent in this randomized controlled trial. Overall, 60 eligible patients were registered based on diagnostic criteria. A brief medical history was gathered, and demographic information was documented. Data on all variables were collected and SPSS version 22 was used to analyze this data.

The mean age, surgical duration, hospital stay duration, height, weight, and body mass index were 48.21±6.24 years, 2.54±1.78 hours, 4±2.54 days, 147±4.21 cm, 71.7±7.25 kg and 28.9±5.14 kg/m2 in the Dextrose group.

Conversely, these parameters were 49.48±8.41 years, 2.97±1.56 hours, 4±1.89 days, 158±5.28 cm, 78.7±9.87 kg, and 29.6±4.91 kg/m2 in the Ringer's lactate group. The effectiveness in preventing post-surgical nausea and vomiting was 80% in the Dextrose group and 36.7% in the Ringer's lactate group.

Preoperative administration of Dextrose reduces the incidence of post-surgical nausea and vomiting in comparison to Ringer's lactate IV solution.