A retrospective cohort study aimed to explore the link between interstitial cystitis and pregnancy and neonatal outcomes with the help of a United States inpatient database.
In this database study comprising of 9,095,995
deliveries, the diagnosis of interstitial cystitis or bladder pain syndrome was found to be linked with higher
rates of preeclampsia, premature birth, and other adverse pregnancy outcomes.
A retrospective cohort study aimed to explore
the link between interstitial cystitis and pregnancy and neonatal outcomes with
the help of a United States inpatient database.
This study was performed using the Nationwide
Inpatient Sample database. The International Classification of Diseases
(ICD)-9 code number 595.1 was used to obtain Chronic Interstitial Cystitis
cases. These pregnancies were later distinguished from the pregnancies without
having interstitial cystitis. The statistically significant confounders were
adjusted via multivariate logistic regression.
During
the study duration, 9,095,995
deliveries were recorded. Chronic interstitial cystitis was observed in 793
pregnant women. Considering the pregnancy outcomes, the diagnosed group was
more prone to developing hypertension due to pregnancy, preeclampsia (toxemia),
preterm delivery, preterm premature rupture of amniotic membranes, chorioamnionitis
(triple I), cesarean section delivery, maternal infection, and deep venous
thromboembolism.
Interstitial cystitis was linked with high
possibilities of poor pregnancy outcomes. To ascertain the association between
interstitial cystitis and unfavourable pregnancy outcomes, future studies are
required.
The Journal of Urology
Interstitial Cystitis/Bladder Pain Syndrome's Correlations with Pregnancy and Neonatal Outcomes: A Study of a Population Database
Mohammad I Khojah et al.
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