In this database study comprising of 9,095,995 deliveries, the diagnosis of interstitial cystitis or bladder pain syndrome was found to be linked with higher rates of preeclampsia, premature birth, and other adverse pregnancy outcomes. 

A retrospective cohort study aimed to explore the link between interstitial cystitis and pregnancy and neonatal outcomes with the help of a United States inpatient database.

This study was performed using the Nationwide Inpatient Sample database. The International Classification of Diseases (ICD)-9 code number 595.1 was used to obtain Chronic Interstitial Cystitis cases. These pregnancies were later distinguished from the pregnancies without having interstitial cystitis. The statistically significant confounders were adjusted via multivariate logistic regression.

During the study duration, 9,095,995 deliveries were recorded. Chronic interstitial cystitis was observed in 793 pregnant women. Considering the pregnancy outcomes, the diagnosed group was more prone to developing hypertension due to pregnancy, preeclampsia (toxemia), preterm delivery, preterm premature rupture of amniotic membranes, chorioamnionitis (triple I), cesarean section delivery, maternal infection, and deep venous thromboembolism.

Interstitial cystitis was linked with high possibilities of poor pregnancy outcomes. To ascertain the association between interstitial cystitis and unfavourable pregnancy outcomes, future studies are required.