In pregnant women undergoing spinal anesthesia during cesarean section, intravenous Tramadol relieves perioperative shivering more quickly than intravenous Pethidine.

A randomized double-blind trial was carried out to examine the effectiveness of Tramadol (anti-shivering drug) vs. Pethidine to treat perioperative shivering in patients undergoing cesarean section under spinal anesthesia.

Overall, 42 parturients with a body mass index of 29.9 ± 4.9 kg/m2  and a mean age of 30.2 ± 5.2 years, experiencing shivering during spinal anesthetic cesarean section were divided into two groups at random. Subjects in Group T were given 1 mg/kg of Tramadol, while subjects in Group P received 0.5 mg/kg of Pethidine. The time taken for shivering to stop after taking the drug, the occurrence of adverse events, and shivering recurrence were among the outcome measures.

As shown in Table 1, the Tramadol group's median time from medication administration till the termination of shivering was faster than that of the Pethidine group.

There was no discernible difference between the two groups in terms of occurrence of nausea and the number of recurrences of shivering episodes.

Hence, 1 mg/kg Tramadol was superior to 0.5 mg/kg Pethidine to control perioperative shivering during cesarean section under spinal anesthesia.