This study examined whether controlled ventilation with MR during airway stenting decreases the occurrence of desaturation events (percutaneous oxygen saturation, Spo2 <95%) in comparison with the use of spontaneous respiration (SP).
Airway stenting is a technique in which a stent is introduced into a stenotic site of the airway. This prospective randomized interventional study addressed the effectiveness and safety of controlled ventilation via muscle relaxants (MR) under anesthesia for airway stenting which will help recognize safest anesthetic techniques for airway stenting. The use of muscle relaxants reduced the incidence of desaturation events thereby sustaining a favourable respiratory status.
This study examined whether controlled ventilation with
MR during airway stenting decreases the occurrence of desaturation events
(percutaneous oxygen saturation, Spo2 <95%) in comparison with the use of
spontaneous respiration (SP).
A total of 64 patients were subjected to the controlled
ventilation were divided into MR or SP group. Total intravenous (IV) anesthesia
via propofol target-controlled infusion and remifentanil was used. Following
the administration of MR, a rigid bronchoscope was inserted to perform
controlled ventilation in the MR group.
The occurrence of desaturation events in the SP and MR groups was 75.0% (24/32) and 9.7% (3/31) as observed in the following table:
The mean intraoperative pH was lower in
the SP group as compared to the MR group. Also, SP group had greater mean partial pressure of arterial
carbon dioxide, Paco2 (70.2 ± 17.0 versus 40.5 ± 8.0 mm Hg) and lesser mean
partial pressure of oxygen in the arterial blood/fraction of the inspiratory
oxygen ratio (263.1 ± 64.2 versus 396.4 ± 69.4 mm Hg).
Desaturation events decreased with the help of controlled
ventilation with MR.
Anesthesia & Analgesia
A Prospective, Randomized Trial Comparing Respiratory Status During Anesthesia for Airway Stenting: Spontaneous Respiration Versus Controlled Ventilation With Muscle Relaxants
Okamoto, Sakura et al.
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