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To examine the effectiveness of MINST of periodontal pockets with or without local treatment of NaOCl gel.
Amino acid buffered sodium hypochlorite (NaOCl) gel
have been known to destroy the microbial biofilm. The use of NaOCl gel plus
minimally invasive nonsurgical therapy (MINST) displayed exceptional clinical outcomes in
patients with untreated periodontitis with deep periodontal pockets.
To examine the effectiveness of MINST of periodontal
pockets with or without local treatment of NaOCl gel.
Overall, 40 untreated patients with
severe/advanced, stage III/IV periodontitis and a slow/moderate rate of
progression (grade A/B) were divided in 2 treatment groups as:
Different clinical parameters - Gingival
recessions (GR); Full-mouth plaque scores (FMPS) and bleeding on probing scores
(BoP); probing depths (PD) and clinical attachment levels (CAL) were evaluated
at starting and at 6 months following the therapy.
The decrease in PD at sites with PD ≥ 5 mm at
baseline was considered as the primary outcome.
Statistically significant differences were found between the two groups concerning the variation in PD and CAL at 6 months. Number of locations with PD greater than equal to 5 mm and BoP (+) reduced considerably (p = 0.001), i.e. from 85.3 to 2.2% in the test group and 81.6 to 7.3% in the control group. At 6 months, statistically significant differences between both the groups were noted. A significant reduction in the likelihood of residual PDs ≥ 5 mm without and with BoP in test group as compared to control group was observed as displayed in the following table:
MINST usage may prove to be a clinically
valuable approach for nonsurgical therapy of periodontal pockets. The usage of
NaOCl gel along with MINST further adds up to improving the clinical outcomes
than MINST alone.
Clinical oral investigations
Changes in clinical parameters following adjunctive local sodium hypochlorite gel in minimally invasive nonsurgical therapy (MINST) of periodontal pockets: a 6-month randomized controlled clinical trial
Vincenzo Iorio-Siciliano et al.
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