H. heilmannii infection is considerably linked with mild chronic gastritis and can be managed with standard anti-H.pylori therapy.

This systematic review and meta-analysis was carried out to determine the histopathological, endoscopic, clinical, and therapeutic features of Helicobacter heilmannii (H. heilmannii).

A thorough systematic search of international databases, including Google Scholar, ISI Web of Science, PubMed, Embase, and Scopus was done to find out pertinent studies. Utilizing comprehensive meta-analysis software, a statistical assessment was carried out after verifying the studies on the basis of inclusion criteria.

The prevalence of H. heilmannii infection was estimated to be 1.9%. H. heilmannii prevalence in the Asian population was higher when compared to western countries (3.1% vs. 1.2%, respectively). About 15.4% of people had both Helicobacter pylori (H. pylori) and H. heilmannii infections. Erosion, hyperplasia, and persistent gastritis were the most typical endoscopic findings.

Furthermore, gastric inflammation in those with H. heilmannii infection was usually chronic, focal, and less active than gastritis triggered by H. pylori. H. heilmannii can be eliminated with traditional H. pylori therapy.

Hence, there is a significant connection between H. heilmannii infection and mild chronic gastritis.