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This study was carried out to determine the link of postinfectious functional dyspepsia (PI-FD) and Helicobacter pylori [H. pylori]) status with clinical profiles and weight loss.
The postinfectious onset in functional dyspepsia is a significant risk factor for weight reduction.
This study was carried out to determine the link of postinfectious functional dyspepsia (PI-FD) and Helicobacter pylori [H. pylori]) status with clinical profiles and weight loss.
Consecutive functional dyspepsia people were evaluated for severity and frequency of symptoms. Based on severity scores, the recruited people were identified as epigastric pain syndrome, postprandial distress syndrome, or the overlap group. Furthermore, postinfectious history and H. pylori status were evaluated.
In a cohort of 459 functional dyspepsia-people, 9% were characterized as having epigastric pain syndrome, 36% as having postprandial distress syndrome, 9% as having epigastric pain syndrome and 55% demonstrated overlap.
The postinfectious onset and positive H. pylori status were experienced by 20% and 14% of people respectively, not considerably differing between the subgroups. The percentage of people experiencing weight loss is shown in Table 1:
In the study, only early satiety severity correlated with highly serious weight loss in the overlap and postprandial distress syndrome group. People with PI-FD were more vulnerable to weight loss (Odds ratio 2.27). H. pylori status was not substantially linked with weight loss.
The postinfectious onset of functional dyspepsia symptoms emerged as a vital risk factor for weight loss. However, it was not linked with the symptom patterns of overlap, postprandial distress syndrome, or epigastric pain syndrome subgroups. People having H. pylori disease were not more likely to encounter weight reduction.
The Journal of Gastroenterology
Postinfectious onset in functional dyspepsia is a risk factor for weight loss
Jolien Schol et al.
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