Assessment of maternofetal outcomes of acute pancreatitis in pregnancy

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Created On: 04/07/2022

A real-world multi-center, retrospective study was conducted to portray the maternofetal outcomes, clinical manifestations, and etiology of acute pancreatitis in pregnancy (APIP).

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Key take away

In pregnant women, raised levels of triglycerides may act as a beneficial marker of severity of acute pancreatitis.

Background

A real-world multi-center, retrospective study was conducted to portray the maternofetal outcomes, clinical manifestations, and etiology of acute pancreatitis in pregnancy (APIP).

Method

A total of 32 pregnant women were examined. Analysis of association between APIP outcomes, laboratory indices, severity, and causes of APIP was done.

Result

Hypertriglyceridemia (56.2%,18/32) and gallstones (28.1%, 9/32) were the most general causes of APIP. Hypertriglyceridemia-elicited APIP was related to a greater rate of severe acute pancreatitis. A positive correlation was witnessed between serum levels of triglycerides and APIP severity.

Abdominal pain (93.7%, 30/32) was found to be the most common presentation of APIP. No fetal or maternal deaths were reported. A significant association between the Apgar scores of the premature neonates at 1, 5, and 10 minutes and the APIP severity of the mother was witnessed.

Conclusion

High triglycerides level may function as a valuable marker of APIP severity. The APIP severity was linked with a greater risk of neonate asphyxia. Appropriate timing of pregnancy termination is crucial for APIP patients.