In COVID-19 patients with short term cognitive impairment, intensive care led to remarkable betterment in their cognition at three months.

A prospective single-center study (CognitiVID) aimed to assess basic cognitive functions following care in intensive care unit (ICU) and after 3 months in post-ICU SARS-CoV-2 infected patients.

In CognitiVID study, 13 SARS-CoV-2-infected people were enrolled and evaluated at baseline and follow-up. Utilizing standardized cognitive assessments, patients were assessed at baseline and at 3 months follow-up. The evolution of the Montgomery and Asberg Depression Scale (MADRS), Dubois five words test, oral naming test, Frontal Assessment Battery (FAB), and Mini Mental State Evaluation (MMSE) was the major outcome ascertained.

All patients had cognitive decline at baseline. However, at 3 months, improvement was observed on 2 out of 5 global tests following Bonferroni correction for multiple testing, as depicted in Table 1:

Intensive care for three months was associated with cognition improvement in SARS-CoV-2 infected people.