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Acetic Acid vs. Gentamicin ear drops for dry ear in chronic suppurative otitis media

dry ear dry ear
dry ear dry ear

To evaluate the effectiveness of two commonly used antibiotic ear drops - Acetic acid and Gentamicin sulphate for the resolution of dry ear in patients with chronic suppurative otitis media (CSOM).

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Key take away

Both Gentamicin 0.3% and Acetic acid 1.5% ear drops are effective in treating chronic otitis media, with similar outcomes for resolving dry ear.

Background

To evaluate the effectiveness of two commonly used antibiotic ear drops - Acetic acid and Gentamicin sulphate for the resolution of dry ear in patients with chronic suppurative otitis media (CSOM).

Method

This randomized controlled trial comprised 80 patients in the age group of 10 to 70 years. The lottery technique (based on inclusion and exclusion criteria) was used to divide the patients into two groups. Patients in Group A [Average (±Standard deviation) age: 32.7 (±17.3) years] received 0.3% Gentamicin topically while those in Group B [Average (±Standard deviation) age: 26.2 (±15.4) years] received 1.5% Acetic acid topically.

Each group had 40 patients. All patients provided informed consent. To prevent the water from entering the ear, the patients were asked to cover their ear canals with earplugs or cotton balls masked by Vaseline. Effectiveness was assessed by observing the resolution of ear discharge, i.e. achieving a dry ear on the 14th day.

Result

In Group A, otorrhoea or ear discharge resolution was attained in 36 (90%) cases and in Group B, it was resolved in 32 (80%) cases. Both groups exhibited statistically similar efficacy.

Conclusion

In patients with CSOM, Acetic acid was equally efficient to Gentamicin in achieving ear discharge control (dry ear).

Source:

RIPHAH- Islamic International Medical College

Article:

Comparison of Topical Acetic Acid and Gentamicin in Achieving Dry Ear in Chronic Suppurative Otitis Media

Authors:

Mirza Khizar Hameed et al.

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