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Fibromyalgia is a commonly
characterized pain condition indicated by widespread chronic pain, fatigue,
sleep disturbances, headache, impaired cognition, anxiety and mood disorders
with unknown aetiology.
The results of this study indicated a higher incidence of depressive
symptoms, headache intensity, and more likely to have a severe headache-related
disability in migraine patients with and without fibromyalgia.
Fibromyalgia is a commonly characterized pain condition indicated by widespread chronic pain, fatigue, sleep disturbances, headache, impaired cognition, anxiety and mood disorders with unknown aetiology. It is more prevalent in females as compared to males. Previous research has reported an association between comorbid fibromyalgia and migraine, that ranges from 18% to 35.6%. It was investigated that central sensitization plays an integral role in fibromyalgia and chronic migraine. These two disorders are thus considered debilitating pain disorders that increases morbidity of other diseases and affects the quality of life in patients if present together.
Rationale behind research
Objective
The present study aims at determining
differences in depressive symptoms, headache intensity and migraine-related
disability in patients with comorbid fibromyalgia and migraine compared to age
and sex matched controls with a migraine only.
Study outcomes
Time Points: Baseline and after
four weeks
Outcomes
Baseline: There were no significant differences observed at baseline.
Study outcomes:
The results of the present
retrospective study indicate a higher prevalence of fibromyalgia in migraine
patients and vice-versa. Higher PHQ-9 and average headache intensity scores
were observed in patients with comorbid fibromyalgia. The patients were more
likely to score in a higher severity category for both the MIDAS and the PHQ-9.
The present study justifies the previous reports of increased headache-related
disability, depression, and headache severity in patients with comorbid
fibromyalgia and migraine as compared to those with a migraine only. The incidence of fibromyalgia
in patients with migraine was correlated with impaired quality of life. The
findings of the study indicate the need for inquiring about comorbid
fibromyalgia as this can be helpful in creating an optimal individualized
treatment plan. The investigation determined that it is essential to screen for
symptoms of fibromyalgia in migraine patients when many depressive symptoms,
severe headache intensity, or severe headache-related disability were
encountered.
The study does not
indicate the association of medication overuse headache in a majority of the
patients having chronic migraine.
It was reported that there could be higher
incidences of depression symptoms in migraine patients with and without
fibromyalgia. Thus, clinicians are advised to screen patients for comorbid
fibromyalgia particularly in patients with moderate to severe depressive
symptoms, high headache intensity and high headache-related disability.
Whealy et al. The Journal of Headache and Pain (2018) 19:61
Fibromyalgia in migraine: a retrospective cohort study
Mark Whealy et al.
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