As per the notification published on 11 August 2021, a novel data concerning the safety of SARS-CoV-2 vaccines in pregnant females has been released and is recommending all people 12 years of age and older get vaccinated against SARS-CoV-2. CDC suggests that these vaccines are effective and safe, and all pregnant females or females who are thinking about conceiving and those breastfeeding should get vaccinated to safeguard themselves from coronavirus infection.

A novel CDC assessment of the current data from the v-safe pregnancy registry investigated early vaccination in pregnancy. As found, no elevated risk of miscarriage was noted among nearly 2,500 pregnant females receiving an mRNA SARS-CoV-2 vaccine prior to 20 weeks of pregnancy. Notably, miscarriage was reported to occur in about 11-16% of pregnancies, and this analysis reported miscarriage rates of around 13% after receiving coronavirus vaccine that demonstrated similarity to the anticipated rate of miscarriage in the general population.

Earlier, the data from 3 safety monitoring systems didn't identify any safety concerns for the pregnant females who got vaccinated late in their pregnancy or for their babies. These findings and the known serious risks of SARS-CoV-2 during pregnancy illustrate that the benefits of receiving coronavirus vaccine for pregnant females outweigh any potential or known risks.

There has been an escalation in the number of pregnant females suffering from SARS-CoV-2 infection. The elevated circulation of the highly infective and  highly transmissible Delta variant, the reduced vaccine uptake by pregnant females, and the elevated risk of serious illness and pregnancy complications associated with SARS-CoV-2 in pregnant females make vaccination of greater urgency.