Whole-body photobiomodulation intervention for four weeks resulted in a substantial decrease in pain and an improvement in quality of life and psychological factors like kinesiophobia and self-effectiveness in fibromyalgia-affected individuals, as deciphered from a randomized clinical trial. Researchers sought to determine the effects of whole-body photobiomodulation with placebo photobiomodulation on pain, functionality and psychological symptoms in 42 individuals suffering from fibromyalgia.

In this triple-blinded, placebo-controlled study, volunteers were given 12 treatment sessions. Quality of life, pain, level of physical activity and psychological factors were evaluated at the baseline, after session 6, after therapy, and at the two-week follow-up. At 4 weeks and the 2-week follow-up, substantial differences in pain were noted. Regarding the quality of life, remarkable improvements were noted after session 6, immediately following treatment, and at the two-week follow-up.

Kinesiophobia illustrated considerable differences between groups immediately post-treatment and at the 2-week follow-up, with self-effectiveness only demonstrating profound differences between groups two weeks after the treatment. When assessing pain catastrophising at any time, no differences were noted between groups.

Hence, whole-body photobiomodulation is a promising novel multifactorial treatment for those with chronic musculoskeletal pain conditions. Additional studies are required for corroborating these findings.