A recent study by Broseler F and colleagues have revealed that periodontal regenerative therapy can lead to long-term defects reduction and tooth survival among patients suffering from periodontal disease. The term periodontal refers to a condition of the structures present around the teeth like alveolar bone, gums, and periodontal ligament. Therefore, in case of periodontal disease, periodontist most of the times, recommends a regenerative procedure to restore periodontal structure and function. Hence, a study was conducted to evaluate the long-term effects of periodontal regenerative therapy in corrections of intra-bony defects.

For the study, a total of 176 patients were analyzed. These patients comprised 1,008 intra-bony defects. They were analyzed after using collagen-added deproteinized bovine bone mineral (DBBMc) with or without collagen membrane (CM) or enamel matrix derivative (EMD). The defects chosen for the study were differently categorized. These were categorized as one and two-wall, shallow, moderate and deep. The bone level changes were evaluated by bone radiography after 1, 2, 4 and 5 to 10 years.

Following one year of treatment, the mean radiographic defect was found to be filled up to 3.8 mm, which remained stable up to the next ten years. The deep and moderate defects showed higher rates of filling than of slight defects. Further, the tooth loss occurred mainly due to endodontic reasons, and its rate of occurrence was based upon defect type. Overall, it was stated that periodontal regenerative therapy leads to long-term defects reduction and tooth survival among patients with periodontal disease.