As per the outcomes of a recent meta-analysis, magnesium sulfate was useful in lowering the  highest visual analog scale (VAS) in women who undertook general anesthesia, spinal anesthesia, or epidural for cesarean section. It also helped in significantly decreasing the postsurgical pain after cesarean section.

Siguang Ma and investigators reviewed the effectiveness of MgSO₄ on improving postsurgical analgesia following cesarean section. The Cochrane library, PubMed, and Embase were explored for the relevant randomized controlled trials.

Overall, 880 women were considered (440 in the MgSO₄ group and 440 in the control group). MgSO₄ had a statistically noteworthy effect than the control group concerning the highest VAS and the last VAS. Patients in the MgSO₄ group had prolonged the time to the initial analgesia usage (standardized mean difference [SMD] = −3.03 min) and lowered analgesia consumption (SMD = −3.20 mg of IV morphine equivalent) than the patients in the control group.