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Unloading knee brace can be considered as an
adjunctive therapy to improve pain and function in patients with medial knee
osteoarthritis (OA).
A recent study conducted in France by nine
private and one hospital-based physician showed that the unloading braces
provide a significant reduction in pain related to knee osteoarthritis.
Unloading knee braces provide extraordinary
relief from arthritis pain. However, evidence regarding its efficacy is still
indefinite. This study was conducted to determine the efficacy of unloading
knee brace in patients with knee OA. The study is a randomized, prospective,
multicenter, controlled, two-arm, parallel-group, open-label, phase III trial
which involved 67 patients having symptomatic knee osteoarthritis. Out of
these, 32 patients placed in the brace group who received usual care with unloading
knee brace treatment. Patients in the control group received only usual care.
The global last 24h-pain relief at 6 weeks was considered as primary endpoint
and function, safety, pain on motion and observance was taken as secondary
endpoints. The visual analogic scale (VAS) was used to measure pain and
Lequesne index to measured function.
The brace group exhibited a significant
reduction in mean last 24h-pain, pain on motion and better Lequesne index score
as compared to the control group at 6 weeks. The observance and safety were
also better among brace group.
Sci Rep.
Effect of unloading brace treatment on pain and function in patients with symptomatic knee osteoarthritis: the ROTOR randomized clinical trial
Philippe Thoumie et al.
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